Reversal of Synapse Degeneration by Restoring Wnt Signaling in the Adult Hippocampus

Synapse degeneration occurs early in neurodegenerative diseases and correlates strongly with cognitive decline in Alzheimer’s disease (AD). The molecular mechanisms that trigger synapse vulnerability and those that promote synapse regeneration after substantial synaptic failure remain poorly underst...

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Publicat a:Curr Biol
Autors principals: Marzo, Aude, Galli, Soledad, Lopes, Douglas, McLeod, Faye, Podpolny, Marina, Segovia-Roldan, Margarita, Ciani, Lorenza, Purro, Silvia, Cacucci, Francesca, Gibb, Alasdair, Salinas, Patricia C.
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070786/
https://ncbi.nlm.nih.gov/pubmed/27593374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2016.07.024
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