Innate Signaling in the CNS Prevents Demyelination in a Focal EAE Model

The pathological hallmark of multiple sclerosis (MS) is the formation of multifocal demyelinating lesions in the central nervous system (CNS). Stimulation of innate receptors has been shown to suppress experimental autoimmune encephalomyelitis (EAE), an MS-like disease in mice. Specifically, targeti...

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Bibliografische gegevens
Gepubliceerd in:Front Neurosci
Hoofdauteurs: Dubik, Magdalena, Marczynska, Joanna, Mørch, Marlene T., Webster, Gill, Jensen, Kirstine Nolling, Wlodarczyk, Agnieszka, Khorooshi, Reza, Owens, Trevor
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2021
Onderwerpen:
Neuroscience
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8209300/
https://ncbi.nlm.nih.gov/pubmed/34149350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2021.682451
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