Interactions between hippocampal activity and striatal dopamine in people at clinical high risk for psychosis: relationship to adverse outcomes

Preclinical models propose that increased hippocampal activity drives subcortical dopaminergic dysfunction and leads to psychosis-like symptoms and behaviors. Here, we used multimodal neuroimaging to examine the relationship between hippocampal regional cerebral blood flow (rCBF) and striatal dopami...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Modinos, Gemma, Richter, Anja, Egerton, Alice, Bonoldi, Ilaria, Azis, Matilda, Antoniades, Mathilde, Bossong, Matthijs, Crossley, Nicolas, Perez, Jesus, Stone, James M., Veronese, Mattia, Zelaya, Fernando, Grace, Anthony A., Howes, Oliver D., Allen, Paul, McGuire, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8209204/
https://ncbi.nlm.nih.gov/pubmed/33941857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-021-01019-0
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