Clobetasol promotes neuromuscular plasticity in mice after motoneuronal loss via sonic hedgehog signaling, immunomodulation and metabolic rebalancing

Motoneuronal loss is the main feature of amyotrophic lateral sclerosis, although pathogenesis is extremely complex involving both neural and muscle cells. In order to translationally engage the sonic hedgehog pathway, which is a promising target for neural regeneration, recent studies have reported...

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Publicado no:Cell Death Dis
Main Authors: Vicario, Nunzio, Spitale, Federica M., Tibullo, Daniele, Giallongo, Cesarina, Amorini, Angela M., Scandura, Grazia, Spoto, Graziana, Saab, Miriam W., D’Aprile, Simona, Alberghina, Cristiana, Mangione, Renata, Bernstock, Joshua D., Botta, Cirino, Gulisano, Massimo, Buratti, Emanuele, Leanza, Giampiero, Zorec, Robert, Vecchio, Michele, Di Rosa, Michelino, Li Volti, Giovanni, Lazzarino, Giuseppe, Parenti, Rosalba, Gulino, Rosario
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8209072/
https://ncbi.nlm.nih.gov/pubmed/34135312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03907-1
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