Cyclooxygenase (COX)-2 modulates Toxoplasma gondii infection, immune response and lipid droplets formation in human trophoblast cells and villous explants

Congenital toxoplasmosis is represented by the transplacental passage of Toxoplasma gondii from the mother to the fetus. Our studies demonstrated that T. gondii developed mechanisms to evade of the host immune response, such as cyclooxygenase (COX)-2 and prostaglandin E(2) (PGE(2)) induction, and th...

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Udgivet i:Sci Rep
Main Authors: de Souza, Guilherme, Silva, Rafaela José, Milián, Iliana Claudia Balga, Rosini, Alessandra Monteiro, de Araújo, Thádia Evelyn, Teixeira, Samuel Cota, Oliveira, Mário Cézar, Franco, Priscila Silva, da Silva, Claudio Vieira, Mineo, José Roberto, Silva, Neide Maria, Ferro, Eloisa Amália Vieira, Barbosa, Bellisa Freitas
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8209052/
https://ncbi.nlm.nih.gov/pubmed/34135407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-92120-3
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