Cyclooxygenase (COX)-2 Inhibitors Reduce Toxoplasma gondii Infection and Upregulate the Pro-inflammatory Immune Response in Calomys callosus Rodents and Human Monocyte Cell Line

Toxoplasma gondii is able to infect a wide range of vertebrates, including humans. Studies show that cyclooxygenase-2 (COX-2) is a modulator of immune response in multiple types of infection, such as Trypanosoma cruzi. However, the role of COX-2 during T. gondii infection is still unclear. The aim o...

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Vydáno v:Front Microbiol
Hlavní autoři: Pereira, Ana Carolina Alcântara, Silva, Rafaela José, Franco, Priscila Silva, de Oliveira Gomes, Angelica, Souza, Guilherme, Milian, Iliana Claudia Balga, Ribeiro, Mayara, Rosini, Alessandra Monteiro, Guirelli, Pâmela Mendonça, Ramos, Eliézer Lucas Pires, Mineo, Tiago Wilson Patriarca, Mineo, José Roberto, Silva, Neide Maria, Ferro, Eloisa Amália Vieira, Barbosa, Bellisa Freitas
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6379304/
https://ncbi.nlm.nih.gov/pubmed/30809216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.00225
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