Amitriptyline functionally antagonizes cardiac H(2) histamine receptors in transgenic mice and human atria

We have previously shown that histamine (2-(1H-imidazol-4-yl)ethanamine) exerted concentration-dependent positive inotropic effects (PIE) or positive chronotropic effects (PCE) on isolated left and right atria, respectively, of transgenic (H(2)R-TG) mice that overexpress the human H(2) histamine rec...

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Detalhes bibliográficos
Publicado no:Naunyn Schmiedebergs Arch Pharmacol
Main Authors: Neumann, Joachim, Binter, Maximilian Benedikt, Fehse, Charlotte, Marušáková, Margaréta, Büxel, Maren Luise, Kirchhefer, Uwe, Hofmann, Britt, Gergs, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2021
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8208937/
https://ncbi.nlm.nih.gov/pubmed/33625558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-021-02065-7
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