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Phosphodiesterases 2, 3 and 4 can decrease cardiac effects of H(2)-histamine-receptor activation in isolated atria of transgenic mice
Histamine exerts cAMP-dependent positive inotropic effects (PIE) and positive chronotropic effects (PCE) on isolated left and right atria, respectively, of transgenic mice which overexpress the human H(2)-receptor in the heart (=H(2)-TG). To determine whether these effects are antagonized by phospho...
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| Publicado no: | Naunyn Schmiedebergs Arch Pharmacol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8208929/ https://ncbi.nlm.nih.gov/pubmed/33576869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-021-02052-y |
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