Transcriptomic Analysis of the Effect of GAT-2 Deficiency on Differentiation of Mice Naïve T Cells Into Th1 Cells In Vitro

The neurotransmitter γ-aminobutyric acid (GABA) is known to affect the activation and function of immune cells. This study investigated the role of GABA transporter (GAT)-2 in the differentiation of type 1 helper T (Th1) cells. Naïve CD4(+) T cells isolated from splenocytes of GAT-2 knockout (KO) an...

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Vydáno v:Front Immunol
Hlavní autoři: Ding, Xueyan, Chang, Yajie, Wang, Siquan, Yan, Dong, Yao, Jiakui, Zhu, Guoqiang
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8208808/
https://ncbi.nlm.nih.gov/pubmed/34149704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.667136
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