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TRIM22 inhibits the TRAF6-stimulated NF-κB pathway by targeting TAB2 for degradation

Tripartite motif containing 22 (TRIM22), a member of the TRIM/RBCC family, has been reported to activate the nuclear factor-kappa B (NF-κB) pathway in unstimulated macrophage cell lines, but the detailed mechanisms governing this activation remains unclear. We investigated this mechanism in HEK293T...

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Bibliografiske detaljer
Udgivet i:Virol Sin
Main Authors: Qiu, Hui, Huang, Fang, Xiao, Han, Sun, Binlian, Yang, Rongge
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8208411/
https://ncbi.nlm.nih.gov/pubmed/23818111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12250-013-3343-4
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