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Analysis of oseltamivir resistance substitutions in influenza virus glycoprotein neuraminidase using a lentivirus-based surrogate assay system

Influenza A virus poses a great threat to global health, and oseltamivir (trade marked as Tamiflu), which targets influenza surface glycoprotein neuraminidase (NA), is used clinically as a major anti-influenza treatment. However, certain substitutions in NA can render an influenza virus resistant to...

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Vydáno v:Virol Sin
Hlavní autoři: Tisoncik-Go, Jennifer, Cordero, Katie S., Rong, Lijun
Médium: Artigo
Jazyk:Inglês
Vydáno: SP Wuhan Institute of Virology, CAS 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8208400/
https://ncbi.nlm.nih.gov/pubmed/23385316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12250-013-3307-8
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