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Mutagenesis of D80-82 and G83 residues in West Nile Virus NS2B: Effects on NS2B-NS3 activity and viral replication
Flaviviral NS2B is a required cofactor for NS3 serine protease activity and plays an important role in promoting functional NS2B-NS3 protease configuration and maintaining critical interactions with protease catalysis substrates. The residues D(80)DDG in West Nile virus (WNV) NS2B are important for...
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| Veröffentlicht in: | Virol Sin |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
SP Wuhan Institute of Virology, CAS
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8208367/ https://ncbi.nlm.nih.gov/pubmed/23325418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12250-013-3276-y |
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