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Effects of NS2B-NS3 protease and furin inhibition on West Nile and Dengue virus replication
West Nile virus (WNV) and Dengue virus (DENV) replication depends on the viral NS2B-NS3 protease and the host enzyme furin, which emerged as potential drug targets. Modification of our previously described WNV protease inhibitors by basic phenylalanine analogs provided compounds with reduced potency...
Enregistré dans:
| Publié dans: | J Enzyme Inhib Med Chem |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6445162/ https://ncbi.nlm.nih.gov/pubmed/28385094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1306521 |
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