UCP1 governs liver extracellular succinate and inflammatory pathogenesis

Non-alcoholic fatty liver disease (NAFLD) is the most prevalent liver pathology worldwide and is intimately linked with obesity and type 2 diabetes. Liver inflammation is a hallmark of NAFLD and is thought to contribute to tissue fibrosis and disease pathogenesis. Uncoupling protein 1 (UCP1) is excl...

Full description

Saved in:
Bibliographic Details
Published in:Nat Metab
Main Authors: Mills, Evanna L., Harmon, Cathal, Jedrychowski, Mark P., Xiao, Haopeng, Garrity, Ryan, Tran, Nhien V., Bradshaw, Gary A., Fu, Accalia, Szpyt, John, Reddy, Anita, Prendeville, Hannah, Danial, Nika N., Gygi, Steven P., Lynch, Lydia, Chouchani, Edward T.
Format: Artigo
Language:Inglês
Published: 2021
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8207988/
https://ncbi.nlm.nih.gov/pubmed/34002097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42255-021-00389-5
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items