Anti-CD20 treatment effectively attenuates cortical pathology in a rat model of widespread cortical demyelination

BACKGROUND: Cortical demyelination represents a prominent feature of the multiple sclerosis (MS) brain, especially in (late) progressive stages. We recently developed a new rat model that reassembles critical features of cortical pathology characteristic to progressive types of MS. In persons affect...

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Veröffentlicht in:J Neuroinflammation
Hauptverfasser: Haindl, Michaela T., Üçal, Muammer, Klaus, Benjamin, Tögl, Lennart, Dohrmann, Jana, Adzemovic, Milena Z., Enzinger, Christian, Hochmeister, Sonja
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8207776/
https://ncbi.nlm.nih.gov/pubmed/34130726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-021-02189-w
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