Effect of Vitamin D on Experimental Autoimmune Neuroinflammation Is Dependent on Haplotypes Comprising Naturally Occurring Allelic Variants of CIITA (Mhc2ta)

An increasing body of evidence associates low vitamin D levels with increased risk of multiple sclerosis (MS), suggesting the possibility of a gene-environment interaction for this environmental factor in MS pathogenesis. Moreover, it has been shown that vitamin D downregulates major histocompatibil...

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Detalhes bibliográficos
Publicado no:Front Neurol
Main Authors: Hochmeister, Sonja, Aeinehband, Shahin, Dorris, Charles, Berglund, Rasmus, Haindl, Michaela T., Velikic, Vid, Gustafsson, Sven A., Olsson, Tomas, Piehl, Fredrik, Jagodic, Maja, Zeitelhofer, Manuel, Adzemovic, Milena Z.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Neurology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693436/
https://ncbi.nlm.nih.gov/pubmed/33304315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2020.600401
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