Identification of monoclonal antibodies against human renal glomerular endothelial cells in lupus nephritis that induce endothelial interferon-alpha production

BACKGROUND: The pathogenesis of lupus nephritis (LN) remains not fully understood. In this study, we aimed to explore the pathogenic roles of autoantibodies against human renal glomerular endothelial cells (HRGEC) in LN patients. METHODS: The serum levels of anti-HRGEC antibodies in systemic lupus e...

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Publicat a:Arthritis Res Ther
Autors principals: Hu, Ya-Chiao, Tsai, I-Jung, Hsu, Hui-Yao, Chiang, Bor-Luen, Yang, Yao-Hsu
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8207712/
https://ncbi.nlm.nih.gov/pubmed/34134755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-021-02552-5
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