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Identification of monoclonal antibodies against human renal glomerular endothelial cells in lupus nephritis that induce endothelial interferon-alpha production

BACKGROUND: The pathogenesis of lupus nephritis (LN) remains not fully understood. In this study, we aimed to explore the pathogenic roles of autoantibodies against human renal glomerular endothelial cells (HRGEC) in LN patients. METHODS: The serum levels of anti-HRGEC antibodies in systemic lupus e...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Hu, Ya-Chiao, Tsai, I-Jung, Hsu, Hui-Yao, Chiang, Bor-Luen, Yang, Yao-Hsu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8207712/
https://ncbi.nlm.nih.gov/pubmed/34134755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-021-02552-5
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