Alzheimer’s Disease: New Concepts on the Role of Autoimmunity and NLRP3 Inflammasome in the Pathogenesis of the Disease

Alzheimer’s disease (AD), recognized as the most common neurodegenerative disorder, is clinically characterized by the presence of extracellular beta-amyloid (Aβ) plaques and by intracellular neurofibrillary tau tangles, accompanied by glial activation and neuroinflammation. Increasing evidence sugg...

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Veröffentlicht in:Curr Neuropharmacol
Hauptverfasser: Severini, Cinzia, Barbato, Christian, Di Certo, Maria Grazia, Gabanella, Francesca, Petrella, Carla, Di Stadio, Arianna, de Vincentiis, Marco, Polimeni, Antonella, Ralli, Massimo, Greco, Antonio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Bentham Science Publishers 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8206463/
https://ncbi.nlm.nih.gov/pubmed/32564756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1570159X18666200621204546
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