A computational approach for detecting physiological homogeneity in the midst of genetic heterogeneity

The human genetic dissection of clinical phenotypes is complicated by genetic heterogeneity. Gene burden approaches that detect genetic signals in case-control studies are underpowered in genetically heterogeneous cohorts. We therefore developed a genome-wide computational method, network-based hete...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Am J Hum Genet
Main Authors: Zhang, Peng, Cobat, Aurélie, Lee, Yoon-Seung, Wu, Yiming, Bayrak, Cigdem Sevim, Boccon-Gibod, Clémentine, Matuozzo, Daniela, Lorenzo, Lazaro, Jain, Aayushee, Boucherit, Soraya, Vallée, Louis, Stüve, Burkhard, Chabrier, Stéphane, Casanova, Jean-Laurent, Abel, Laurent, Zhang, Shen-Ying, Itan, Yuval
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8206396/
https://ncbi.nlm.nih.gov/pubmed/34015270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2021.04.023
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados