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Clinical Pharmacokinetics of Oral Sodium Selenite and Dosing Implications in the Treatment of Patients with Metastatic Cancer

BACKGROUND: Selenite is a radiosensitizer and inhibitor of androgen receptor expression and function. In a phase I study (NCT02184533) in 15 subjects with metastatic cancer receiving daily oral sodium selenite with palliative radiation therapy, disease stabilization was observed, as evidenced by tum...

詳細記述

保存先:
書誌詳細
出版年:Drugs R D
主要な著者: Jayachandran, Priya, Knox, Susan J., Garcia-Cremades, Maria, Savić, Radojka M.
フォーマット: Artigo
言語:Inglês
出版事項: Springer International Publishing 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8206290/
https://ncbi.nlm.nih.gov/pubmed/33866531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40268-021-00340-9
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