Generation of patterned kidney organoids that recapitulate the adult kidney collecting duct system from expandable ureteric bud progenitors

Current kidney organoids model development and diseases of the nephron but not the contiguous epithelial network of the kidney’s collecting duct (CD) system. Here, we report the generation of an expandable, 3D branching ureteric bud (UB) organoid culture model that can be derived from primary UB pro...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Zeng, Zipeng, Huang, Biao, Parvez, Riana K., Li, Yidan, Chen, Jyunhao, Vonk, Ariel C., Thornton, Matthew E., Patel, Tadrushi, Rutledge, Elisabeth A., Kim, Albert D., Yu, Jingying, Grubbs, Brendan H., McMahon, Jill A., Pastor-Soler, Nuria M., Hallows, Kenneth R., McMahon, Andrew P., Li, Zhongwei
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8206157/
https://ncbi.nlm.nih.gov/pubmed/34131121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23911-5
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