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Morphogenesis of the kidney and lung requires branch-tip directed activity of the Adamts18 metalloprotease

Adamts18 encodes a secreted metalloprotease restricted to branch-tip progenitor pools directing the morphogenesis of multiple mammalian organs. Adamts18 was targeted to explore a potential role in branching morphogenesis. In the kidney, an arborized collecting system develops through extensive branc...

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Dettagli Bibliografici
Pubblicato in:Dev Biol
Autori principali: Rutledge, Elisabeth A., Parvez, Riana K., Short, Kieran M., Smyth, Ian M., McMahon, Andrew P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726516/
https://ncbi.nlm.nih.gov/pubmed/31242448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2019.06.012
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