DNA methylation at birth potentially mediates the association between prenatal lead (Pb) exposure and infant neurodevelopmental outcomes

Early-life lead (Pb) exposure has been linked to adverse neurodevelopmental outcomes. Recent evidence has indicated a critical role of DNA methylation (DNAm) in cognition, and Pb exposure has also been shown to alter DNAm. However, it is unknown whether DNAm is part of the mechanism of Pb neurotoxic...

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Udgivet i:Environ Epigenet
Main Authors: Rygiel, Christine A, Dolinoy, Dana C, Bakulski, Kelly M, Aung, Max T, Perng, Wei, Jones, Tamara R, Solano-González, Maritsa, Hu, Howard, Tellez-Rojo, Martha M, Schnaas, Lourdes, Marcela, Erika, Peterson, Karen E, Goodrich, Jaclyn M
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8206046/
https://ncbi.nlm.nih.gov/pubmed/34141453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eep/dvab005
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