Prenatal Lead (Pb) Exposure and Peripheral Blood DNA Methylation (5mC) and Hydroxymethylation (5hmC) in Mexican Adolescents from the ELEMENT Birth Cohort

BACKGROUND: Gestational lead (Pb) exposure can adversely affect offspring health through multiple mechanisms, including epigenomic alterations via DNA methylation (5mC) and hydroxymethylation (5hmC), an intermediate in oxidative demethylation. Most current methods do not distinguish between 5mC and...

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Publicado no:Environ Health Perspect
Main Authors: Rygiel, Christine A., Goodrich, Jaclyn M., Solano-González, Maritsa, Mercado-García, Adriana, Hu, Howard, Téllez-Rojo, Martha M., Peterson, Karen E., Dolinoy, Dana C.
Formato: Artigo
Idioma:Inglês
Publicado em: Environmental Health Perspectives 2021
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8216410/
https://ncbi.nlm.nih.gov/pubmed/34152198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/EHP8507
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