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PARP1: Structural Insights and Pharmacological Targets for Inhibition
Poly(ADP-ribose) polymerase 1 (PARP1, also known as ADPRT1) is a multifunctional human ADP-ribosyltransferase. It plays a role in multiple DNA repair pathways, including the base excision repair (BER), non-homologous end joining (NHEJ), homologous recombination (HR), and Okazaki-fragment processing...
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| 出版年: | DNA Repair (Amst) |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8206044/ https://ncbi.nlm.nih.gov/pubmed/33940558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2021.103125 |
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