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Systemic manifestation and contribution of peripheral tissues to Huntington’s disease pathogenesis
Huntington disease (HD) is an autosomal dominant neurodegenerative disease that is caused by expansion of cytosine/adenosine/guanine repeats in the huntingtin (HTT) gene, which leads to a toxic, aggregation-prone, mutant HTT-polyQ protein. Beyond the well-established mechanisms of HD progression in...
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| Publicado no: | Ageing Res Rev |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8205985/ https://ncbi.nlm.nih.gov/pubmed/33979693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.arr.2021.101358 |
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