Achieving Target Infliximab Drug Concentrations Improves Blood and Fecal Neutrophil Biomarkers in Crohn’s Disease

BACKGROUND: The neutrophil fecal biomarkers, calprotectin (FCP) and lactoferrin (LCT), and peripheral blood neutrophil CD64 surface receptor (nCD64) are biomarkers for mucosal inflammation in inflammatory bowel disease (IBD). Although FCP has been evaluated as a biomarker for mucosal healing, cut po...

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Dettagli Bibliografici
Pubblicato in:Inflamm Bowel Dis
Autori principali: Colman, Ruben J, Tsai, Yi-Ting, Jackson, Kimberly, Boyle, Brendan M, Noe, Joshua D, Hyams, Jeffrey S, D’Haens, Geert R A M, van Limbergen, Johan, Rosen, Michael J, Denson, Lee A, Minar, Phillip
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
Clinical Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8205636/
https://ncbi.nlm.nih.gov/pubmed/32944769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ibd/izaa241
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