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Development of Infliximab Target Concentrations during Induction in Pediatric Crohn’s Disease Patients

OBJECTIVES: Subtherapeutic drug concentrations contribute to both primary and secondary nonresponse to infliximab in children with Crohn’s disease (CD). The aim of this study was to evaluate treatment outcomes and infliximab concentrations at infusions 2 and 3 with an objective to establish inflixim...

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Detalhes bibliográficos
Publicado no:J Pediatr Gastroenterol Nutr
Main Authors: Clarkston, Kathryn, Tsai, Yi-Ting, Jackson, Kimberly, Rosen, Michael J., Denson, Lee A., Minar, Phillip
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6607916/
https://ncbi.nlm.nih.gov/pubmed/31232885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPG.0000000000002304
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