PAR2 Deficiency Induces Mitochondrial ROS Generation and Dysfunctions, Leading to the Inhibition of Adipocyte Differentiation

Protease-activated receptor 2 (PAR2) is a member of G-protein-coupled receptors and affects ligand-modulated calcium signaling. Although PAR2 signaling promotes obesity and adipose tissue inflammation in high fat- (HF-) fed conditions, its role in adipocyte differentiation under nonobesogenic condit...

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Dettagli Bibliografici
Pubblicato in:Oxid Med Cell Longev
Autori principali: Park, Yeo Jin, Lee, Bonggi, Kim, Dae Hyun, Kwon, Eun-Bin, Go, Younghoon, Ha, Sugyeong, Lee, Min-Kyeong, Yu, Hak Sun, Chung, Hae Young
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2021
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8205587/
https://ncbi.nlm.nih.gov/pubmed/34211632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/6683033
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