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Adipocyte-Mineralocorticoid Receptor Alters Mitochondrial Quality Control Leading to Mitochondrial Dysfunction and Senescence of Visceral Adipose Tissue

Mineralocorticoid receptor (MR) expression is increased in the adipose tissue (AT) of obese patients and animals. We previously demonstrated that adipocyte-MR overexpression in mice (Adipo-MROE mice) is associated with metabolic alterations. Moreover, we showed that MR regulates mitochondrial dysfun...

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Bibliografische gegevens
Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Lefranc, Clara, Friederich-Persson, Malou, Foufelle, Fabienne, Nguyen Dinh Cat, Aurélie, Jaisser, Frédéric
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8001019/
https://ncbi.nlm.nih.gov/pubmed/33809055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22062881
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