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Adipocyte-Mineralocorticoid Receptor Alters Mitochondrial Quality Control Leading to Mitochondrial Dysfunction and Senescence of Visceral Adipose Tissue

Mineralocorticoid receptor (MR) expression is increased in the adipose tissue (AT) of obese patients and animals. We previously demonstrated that adipocyte-MR overexpression in mice (Adipo-MROE mice) is associated with metabolic alterations. Moreover, we showed that MR regulates mitochondrial dysfun...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Lefranc, Clara, Friederich-Persson, Malou, Foufelle, Fabienne, Nguyen Dinh Cat, Aurélie, Jaisser, Frédéric
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8001019/
https://ncbi.nlm.nih.gov/pubmed/33809055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22062881
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