Metabolism of the Selective Matrix Metalloproteinase-9 Inhibitor (R)-ND-336

[Image: see text] (R)-ND-336—designated as compound (R)-5—is a highly selective inhibitor of matrix metalloproteinase (MMP)-9 with efficacy in accelerating diabetic wound healing in murine models. (R)-ND-336 belongs to the class of thiirane inhibitors of MMPs and it is currently undergoing Investiga...

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Detalhes bibliográficos
Publicado no:ACS Pharmacol Transl Sci
Main Authors: Gabriel, Charles Edwin Raja, Nguyen, Trung T., Gargano, Emanuele Marco, Fisher, Jed F., Chang, Mayland, Mobashery, Shahriar
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2021
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8205245/
https://ncbi.nlm.nih.gov/pubmed/34151210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.1c00063
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