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High-throughput genotyping of high-homology mutant mouse strains by next-generation sequencing
Genotyping of knockout alleles in mice is commonly performed by end-point PCR or gene-specific/universal cassette qPCR. Both have advantages and limitations in terms of assay design and interpretation of results. As an alternative method for high-throughput genotyping, we investigated next generatio...
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| Publicado no: | Methods |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Academic Press
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8205115/ https://ncbi.nlm.nih.gov/pubmed/33096238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2020.10.011 |
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