Novel CD123 polyaptamer hydrogel edited by Cas9/sgRNA for AML-targeted therapy

CD123 targeting molecules have been widely applied in acute myelocytic leukemia (AML) therapeutics. Although antibodies have been more widely used as targeting molecules, aptamer have unique advantages for CD123 targeting therapy. In this study, we constructed an aptamer hydrogel termed as SSFH whic...

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Detalhes bibliográficos
Publicado no:Drug Deliv
Main Authors: Wu, Haibin, Zhang, Liyu, Zhu, Zeen, Ding, Chenxi, Chen, Shengquan, Liu, Ruiping, Fan, Huafeng, Chen, Yang, Li, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8205012/
https://ncbi.nlm.nih.gov/pubmed/34121564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2021.1934191
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