Novel CD123 polyaptamer hydrogel edited by Cas9/sgRNA for AML-targeted therapy

CD123 targeting molecules have been widely applied in acute myelocytic leukemia (AML) therapeutics. Although antibodies have been more widely used as targeting molecules, aptamer have unique advantages for CD123 targeting therapy. In this study, we constructed an aptamer hydrogel termed as SSFH whic...

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Bibliographic Details
Published in:Drug Deliv
Main Authors: Wu, Haibin, Zhang, Liyu, Zhu, Zeen, Ding, Chenxi, Chen, Shengquan, Liu, Ruiping, Fan, Huafeng, Chen, Yang, Li, Hui
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2021
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8205012/
https://ncbi.nlm.nih.gov/pubmed/34121564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2021.1934191
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