Novel CD123 polyaptamer hydrogel edited by Cas9/sgRNA for AML-targeted therapy

CD123 targeting molecules have been widely applied in acute myelocytic leukemia (AML) therapeutics. Although antibodies have been more widely used as targeting molecules, aptamer have unique advantages for CD123 targeting therapy. In this study, we constructed an aptamer hydrogel termed as SSFH whic...

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Vydáno v:Drug Deliv
Hlavní autoři: Wu, Haibin, Zhang, Liyu, Zhu, Zeen, Ding, Chenxi, Chen, Shengquan, Liu, Ruiping, Fan, Huafeng, Chen, Yang, Li, Hui
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8205012/
https://ncbi.nlm.nih.gov/pubmed/34121564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2021.1934191
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