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Structural basis of TRAPPIII‐mediated Rab1 activation
The GTPase Rab1 is a master regulator of the early secretory pathway and is critical for autophagy. Rab1 activation is controlled by its guanine nucleotide exchange factor, the multisubunit TRAPPIII complex. Here, we report the 3.7 Å cryo‐EM structure of the Saccharomyces cerevisiae TRAPPIII complex...
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| Publicado no: | EMBO J |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8204860/ https://ncbi.nlm.nih.gov/pubmed/34018207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020107607 |
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