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The TRAPPIII complex activates the GTPase Ypt1 (Rab1) in the secretory pathway

Rab GTPases serve as molecular switches to regulate eukaryotic membrane trafficking pathways. The transport protein particle (TRAPP) complexes activate Rab GTPases by catalyzing GDP/GTP nucleotide exchange. In mammalian cells, there are two distinct TRAPP complexes, yet in budding yeast, four distin...

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Detalles Bibliográficos
Publicado en:J Cell Biol
Main Authors: Thomas, Laura L., Joiner, Aaron M.N., Fromme, J. Christopher
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748984/
https://ncbi.nlm.nih.gov/pubmed/29109089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201705214
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