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Structure-based Method for Predicting Deleterious Missense SNPs

Missense SNPs are key factors contributing towards many Mendelian disorders and complex diseases. Identifying whether a single amino acid substitution will lead to pathological effects is important for interpreting personal genome and for precision medicine. In this study, we describe a novel method...

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Detalhes bibliográficos
Publicado no:IEEE EMBS Int Conf Biomed Health Inform
Main Authors: Wang, Boshen, Tian, Wei, Lei, Xue, Perez-Rathke, Alan, Yuan Tseng, Yan, Liang, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8204715/
https://ncbi.nlm.nih.gov/pubmed/34136829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/bhi.2019.8834504
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