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TOP: Time-to-Event Bayesian Optimal Phase II Trial Design for Cancer Immunotherapy

BACKGROUND: Immunotherapies have revolutionized cancer treatment. Unlike chemotherapies, immune agents often take longer to show benefit, and the complex and unique mechanism of action of these agents renders the use of multiple endpoints more appropriate in some trials. These new features of immuno...

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Foilsithe in:J Natl Cancer Inst
Main Authors: Lin, Ruitao, Coleman, Robert L, Yuan, Ying
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8204709/
https://ncbi.nlm.nih.gov/pubmed/30924863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djz049
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