Hyperglycemia minimally alters primary self-renewing human colonic epithelial cells while TNFα-promotes severe intestinal epithelial dysfunction

Hyperglycemia is thought to increase production of inflammatory cytokines and permeability of the large intestine. Resulting intestinal inflammation is then often characterized by excess secretion of tumor necrosis factor alpha (TNFα). Thus, hyperglycemia in hospitalized patients suffering from seve...

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Publicado en:Integr Biol (Camb)
Autores principales: Dutton, Johanna S, Hinman, Samuel S, Kim, Raehyun, Attayek, Peter J, Maurer, Mallory, Sims, Christopher S, Allbritton, Nancy L
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2021
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8204630/
https://ncbi.nlm.nih.gov/pubmed/33989405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intbio/zyab008
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