Clinical and experimental phenotype of azole-resistant Aspergillus fumigatus with a HapE splice site mutation: a case report

BACKGROUND: The recent increase in cases of azole-resistant Aspergillus fumigatus (ARAf) infections is a major clinical concern owing to its treatment limitations. Patient-derived ARAf occurs after prolonged azole treatment in patients with aspergillosis and involves various cyp51A point mutations o...

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Detalhes bibliográficos
Publicado no:BMC Infect Dis
Main Authors: Ito, Yuya, Takazono, Takahiro, Koga, Satoru, Nakano, Yuichiro, Ashizawa, Nobuyuki, Hirayama, Tatsuro, Tashiro, Masato, Saijo, Tomomi, Yamamoto, Kazuko, Imamura, Yoshifumi, Miyazaki, Taiga, Yanagihara, Katsunori, Izumikawa, Koichi, Mukae, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8204526/
https://ncbi.nlm.nih.gov/pubmed/34126952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-021-06279-1
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