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Enzymatic β-Oxidation of the Cholesterol Side Chain in Mycobacterium tuberculosis Bifurcates Stereospecifically at Hydration of 3-Oxo-cholest-4,22-dien-24-oyl-CoA
[Image: see text] The unique ability of Mycobacterium tuberculosis (Mtb) to utilize host lipids such as cholesterol for survival, persistence, and virulence has made the metabolic pathway of cholesterol an area of great interest for therapeutics development. Herein, we identify and characterize two...
Shranjeno v:
| izdano v: | ACS Infect Dis |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Chemical
Society
2021
|
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8204306/ https://ncbi.nlm.nih.gov/pubmed/33826843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.1c00069 |
| Oznake: |
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