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Discovery of SARS-CoV-2 main protease inhibitors using a synthesis-directed de novo design model
The SARS-CoV-2 main viral protease (M(pro)) is an attractive target for antivirals given its distinctiveness from host proteases, essentiality in the viral life cycle and conservation across coronaviridae. We launched the COVID Moonshot initiative to rapidly develop patent-free antivirals with open...
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| Publicado no: | Chem Commun (Camb) |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society of Chemistry
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8204246/ https://ncbi.nlm.nih.gov/pubmed/34008627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d1cc00050k |
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