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Centromere Chromosome Orientation Fluorescent in situ Hybridization (Cen-CO-FISH) Detects Sister Chromatid Exchange at the Centromere in Human Cells

Human centromeres are composed of large tandem arrays of repetitive alpha satellite DNA, which are often sites of aberrant rearrangement in cancers ( Mitelman et al., 1997 ; Padilla- Nash et al., 2001 ). To date, annotation of the human centromere repetitive sequences remains incomplete, greatly hin...

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Dades bibliogràfiques
Publicat a:Bio Protoc
Autor principal: Giunta, Simona
Format: Artigo
Idioma:Inglês
Publicat: Bio-Protocol 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8204152/
https://ncbi.nlm.nih.gov/pubmed/34179295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.2792
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