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Centromere Chromosome Orientation Fluorescent in situ Hybridization (Cen-CO-FISH) Detects Sister Chromatid Exchange at the Centromere in Human Cells

Human centromeres are composed of large tandem arrays of repetitive alpha satellite DNA, which are often sites of aberrant rearrangement in cancers ( Mitelman et al., 1997 ; Padilla- Nash et al., 2001 ). To date, annotation of the human centromere repetitive sequences remains incomplete, greatly hin...

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Bibliografiske detaljer
Udgivet i:Bio Protoc
Hovedforfatter: Giunta, Simona
Format: Artigo
Sprog:Inglês
Udgivet: Bio-Protocol 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8204152/
https://ncbi.nlm.nih.gov/pubmed/34179295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.2792
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