Optogenetically-induced multimerization of the dopamine transporter increases uptake and trafficking to the plasma membrane

The dopamine transporter (DAT) is essential for the reuptake of the released neurotransmitter dopamine (DA) in the brain. Psychostimulants, methamphetamine and cocaine, have been reported to induce the formation of DAT multimeric complexes in vivo and in vitro. The interpretation of DAT multimer fun...

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Vydáno v:J Biol Chem
Hlavní autoři: Ingram, Shalonda M., Rana, Tanu, Manson, Ashley M., Yayah, Faisal M., Jackson, Evan G.B., Anderson, Christopher, Davids, Benem-Orom, Goodwin, J. Shawn
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8203837/
https://ncbi.nlm.nih.gov/pubmed/34015332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100787
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