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Extracellular histones are the ligands for the uptake of exosomes and hydroxyapatite-nanoparticles by tumor cells via syndecan-4

The mechanisms by which exosomes (nano-vesicular messengers of cells) are taken up by recipient cells are poorly understood. We hypothesized that histones associated with these nano-particles are the ligands which facilitate their interaction with cell surface syndecan-4 (SDC4) to mediate their upta...

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Detalhes bibliográficos
Publicado no:FEBS Lett
Main Authors: Ochieng, Josiah, Nangami, Gladys, Sakwe, Amos, Rana, Tanu, Ingram, Shalonda, Goodwin, J. Shawn, Moye, Cierra, Lammers, Philip, Adunyah, Samuel E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6188801/
https://ncbi.nlm.nih.gov/pubmed/30179249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13236
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