Fetuin-A associates with histones intracellularly and shuttles them to exosomes to promote focal adhesion assembly resulting in rapid adhesion and spreading in breast carcinoma cells

The present analyses were undertaken to define the mechanisms by which fetuin-A modulates cellular adhesion. FLAG-tagged fetuin-A was expressed in breast carcinoma and HEK-293T cells. We demonstrated by confocal microscopy that fetuin-A co-localizes with histone H2A in the cell nucleus, forms stable...

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Detalles Bibliográficos
Publicado en:Exp Cell Res
Main Authors: Nangami, Gladys, Koumangoye, Rainelli, Goodwin, J. Shawn, Sakwe, Amos M., Marshall, Dana, Higginbotham, James, Ochieng, Josiah
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253910/
https://ncbi.nlm.nih.gov/pubmed/25194507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2014.08.037
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