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Fetuin-A associates with histones intracellularly and shuttles them to exosomes to promote focal adhesion assembly resulting in rapid adhesion and spreading in breast carcinoma cells

The present analyses were undertaken to define the mechanisms by which fetuin-A modulates cellular adhesion. FLAG-tagged fetuin-A was expressed in breast carcinoma and HEK-293T cells. We demonstrated by confocal microscopy that fetuin-A co-localizes with histone H2A in the cell nucleus, forms stable...

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Bibliografische gegevens
Gepubliceerd in:Exp Cell Res
Hoofdauteurs: Nangami, Gladys, Koumangoye, Rainelli, Goodwin, J. Shawn, Sakwe, Amos M., Marshall, Dana, Higginbotham, James, Ochieng, Josiah
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253910/
https://ncbi.nlm.nih.gov/pubmed/25194507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2014.08.037
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