The power and promise of genetic mapping from Plasmodium falciparum crosses utilizing human liver-chimeric mice

Genetic crosses are most powerful for linkage analysis when progeny numbers are high, parental alleles segregate evenly and numbers of inbred progeny are minimized. We previously developed a novel genetic crossing platform for the human malaria parasite Plasmodium falciparum, an obligately sexual, h...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Button-Simons, Katrina A., Kumar, Sudhir, Carmago, Nelly, Haile, Meseret T., Jett, Catherine, Checkley, Lisa A., Kennedy, Spencer Y., Pinapati, Richard S., Shoue, Douglas A., McDew-White, Marina, Li, Xue, Nosten, François H., Kappe, Stefan H., Anderson, Timothy J. C., Romero-Severson, Jeanne, Ferdig, Michael T., Emrich, Scott J., Vaughan, Ashley M., Cheeseman, Ian H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8203791/
https://ncbi.nlm.nih.gov/pubmed/34127785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-02210-1
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