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Predicting functional and regulatory divergence of a drug resistance transporter gene in the human malaria parasite
BACKGROUND: The paradigm of resistance evolution to chemotherapeutic agents is that a key coding mutation in a specific gene drives resistance to a particular drug. In the case of resistance to the anti-malarial drug chloroquine (CQ), a specific mutation in the transporter pfcrt is associated with r...
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| Publicado no: | BMC Genomics |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4352545/ https://ncbi.nlm.nih.gov/pubmed/25765049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1261-6 |
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